Zacatecas museums and galleries display works of high historical and cultural value. With more than 20 venues to choose from, there is something for most every taste and interest.

The Pedro Coronel Museum, located in the former Jesuit college of San Luis Gonzaga, exhibits Egyptian, Greek, Roman, Indian, Chinese, Japanese, Mayan, Aztec, and African pieces as well as paintings by Picasso, Braque, Delacroix, Dali, Léger, Vasarely, and Miró.

In a similar type of building, the Rafael Coronel Museum has the world's largest collection of masks.  

Other highly recommended museums include the Manuel Felguérez gallery, with a large body of work by the artist of the same name; the Francisco Goytia Museum; the Episcopal Gallery, with religious art belonging to the diocese of Zacatecas; the Toma de Zacatecas Museum, focusing on the battle for Zacatecas during the Revolution; and the Zig-Zag Interactive Science Museum.